Interacción entre ejercicio, dieta hiperproteica, suplementos y AINEs: efectos en la función renal

Contenido principal del artículo

MD Paula Barrantes-Silman
MD Alexis Castillo-Cordero
MD María Céspedes-Valverde
MD Diego Delgado-Gómez
MD Ariel Jimenez-Rivera
MD Juan Santillan-Zúñiga

Keywords

riñón, ejercicio, proteína, suplementos, AINES

Resumen

En la actualidad, se ha observado un incremento notable en la utilización de suplementos dietéticos, como los derivados de creatina, esteroides anabólicos, hormona de crecimiento y AINEs, acompañado de la adopción de dietas hiperproteicas y programas de ejercicio intensivo. Sin embargo, prevalece una amplia desinformación en este ámbito. El empleo no terapéutico de suplementos o su combinación con fármacos nefrotóxicos puede inducir o agravar patologías renales preexistentes, destacando la glomeruloesclerosis focal y segmentaria como la lesión más comúnmente identificada. En relación con el uso excesivo de AINEs, la inhibición de la síntesis de prostaglandinas conlleva principalmente a nefritis intersticial. En la mayoría de los pacientes sin patología renal subyacente, la adopción de dietas ricas en proteínas y la utilización moderada de suplementos para el desarrollo muscular no suscitan problemas renales, siempre y cuando se sigan las pautas de dosificación recomendadas.

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