Premature ovarian failure secondary to mosaicism of Turner syndrome: a case Report
Main Article Content
Keywords
amenorrhea, primary ovarian failure, mosaicism, Turner syndrome
Abstract
Premature ovarian failure (POF) is a syndrome characterized by primary or secondary amenorrhea, hypergonadotropinemia and hypoestrogenism. This clinical condition may be due to multiple etiologies; however, it is idiopathic in most cases. It is a benign condition, but with important repercussions in the reproductive sphere and general condition. The diagnostic in patients with amenorrhea includes a thorough anamnesis and physical examination, as well as multiple laboratorial and imaging tests. Generally, estradiol levels are below 50pg / ml and FSH levels above 40mIU / ml. Within the studies to be carried out in cases of amenorrhea, the karyotype is included. In cases of Turner syndrome, primary amenorrhea is the rule, however in Turner mosaicisms the phenotype can be varied, including amenorrhea or spontaneous menstruation according to the percentage of 46XX and 45X cell lines.
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