Sarcopenia en paciente oncológico: revisión de literatura
Contenido principal del artículo
Keywords
Sarcopenia, Neoplasias, Debilidad Muscular
Resumen
El cáncer es una patología cada vez más común que genera altos grados de desgaste físico, emocional y psicosocial en quienes la padecen, además de importantes costos económicos para los servicios de salud. La sarcopenia, una condición caracterizada por la pérdida de masa, fuerza y función muscular de etiología multifactorial, es un factor de mal pronóstico en pacientes oncológicos. Esta afección impacta variables como las readmisiones hospitalarias postquirúrgicas, estancias prolongadas, alteración en el proceso de cicatrización, y disminución de la calidad de vida y funcionalidad. Este artículo presenta una revisión actualizada del tema y enfatiza la importancia de identificar a los pacientes con alto riesgo de desarrollar sarcopenia, con el objetivo de implementar medidas tempranas y esquemas de tratamiento oportuno.
Citas
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3. Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, et al.; Writing Group for the European Working Group on Sarcopenia in Older People 2 (EWGSOP2), and the Extended Group for EWGSOP2. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(1):16-31. Doi: 10.1093/ageing/afy169
4. Peterson SJ, Braunschweig CA. Prevalence of Sarcopenia and Associated Outcomes in the Clinical Setting. Nutr Clin Pract. 2016;31(1):40-48. Doi: 10.1177/0884533615622537
5. Barret M, Antoun S, Dalban C, Malka D, Mansourbakht T, Zaanan A, et al. Sarcopenia is linked to treatment toxicity in patients with metastatic colorectal cancer. Nutr Cancer. 2014;66(4):583-589. Doi: 10.1080/01635581.2014.894103
6. da Silva JR Jr, Wiegert E, Oliveira L, Calixto-Lima L. Different methods for diagnosis of sarcopenia and its association with nutritional status and survival in patients with advanced cancer in palliative care. Nutrition. 2019;60:48-52. Doi: 10.1016/j.nut.2018.09.003
7. Pamoukdjian F, Bouillet T, Lévy V, Soussan M, Zelek L, Paillaud E. Prevalence and predictive value of pre-therapeutic sarcopenia in cancer patients: A systematic review. Clin Nutr. 2018;37(4):1101-1113. Doi: 10.1016/j.clnu.2017.07.010
8. Molina Garrido MJ, Guillén Ponce C, Fernández Félix B, Muñoz Sánchez M, Soriano Rodríguez M, Olaverri Hernández A, et al. Detección y evaluación del papel de la sarcopenia en ancianos con cáncer tratados con quimioterapia. Proyecto ONCOSARCO. Rev Esp Geriatr Gerontol. 2017;52(3):146-151. Doi: 10.1016/j.regg.2016.02.003
9. Chindapasirt J. Sarcopenia in Cancer Patients. Asian Pac J Cancer Prev. 2015;16(18):8075-8077. Doi: 10.7314/apjcp.2015.16.18.8075
10. Kazemi-Bajestani SM, Mazurak VC, Baracos V. Computed tomography-defined muscle and fat wasting are associated with cancer clinical outcomes. Semin Cell Dev Biol. 2016;54:2-10. Doi: 10.1016/j.semcdb.2015.09.001
11. da Cunha LP, Silveira MN, Mendes M, Costa FO, Macedo LT, de Siqueira NS, et al. Sarcopenia as an independent prognostic factor in patients with metastatic colorectal cancer: A retrospective evaluation. Clin Nutr ESPEN. 2019;32:107-112. Doi: 10.1016/j.clnesp.2019.04.004
12. Uchida T, Sekine R, Matsuo K, Kigawa G, Umemoto T, Kijima K, et al. Association between low preoperative skeletal muscle quality and infectious complications following gastrectomy for gastric cancer. Surg Today. 2021;51(7):1135-1143. Doi: 10.1007/s00595-020-02225-x
13. Fuggle N, Shaw S, Dennison E, Cooper C. Sarcopenia. Best Pract Res Clin Rheumatol. 2017;31(2):218-242. Doi: 10.1016/j.berh.2017.11.007
14. Robertson HL, Michel C, Bartl L, Hamilton-Reeves JM. Sarcopenia in urologic oncology: Identification and strategies to improve patient outcomes. Urol Oncol. 2020;S1078-1439(20)30197-6. Advance online publication. Doi: 10.1016/j.urolonc.2020.05.001
15. Narayan V, Harrison M, Cheng H, Kenfield S, Aggarwal R, Kwon D, et al. Improving research for prostate cancer survivorship: A statement from the Survivorship Research in Prostate Cancer (SuRECaP) working group. Urol Oncol. 2020;38(3):83-93. Doi: 10.1016/j.urolonc.2019.10.006
16. Martínez-González MA, Sánchez-Villegas A. Food patterns and the prevention of depression. Proc Nutr Soc. 2016;75(2):139-146. Doi: 10.1017/S0029665116000045
17. Shachar SS, Williams GR, Muss HB, Nishijima TF. Prognostic value of sarcopenia in adults with solid tumours: A meta-analysis and systematic review. Eur J Cancer. 2016;57:58-67. Doi: 10.1016/j.ejca.2015.12.030
18. Krznarić Ž, Bender DV, Laviano A, Cuerda C, Landi F, Monteiro R, et al. A simple remote nutritional screening tool and practical guidance for nutritional care in primary practice during the COVID-19 pandemic. Clin Nutr. 2020;39(7):1983-1987. Doi: 10.1016/j.clnu.2020.05.006
19. Malmstrom TK, Miller DK, Simonsick EM, Ferrucci L, Morley JE. SARC-F: a symptom score to predict persons with sarcopenia at risk for poor functional outcomes. J Cachexia Sarcopenia Muscle. 2016;7(1):28-36. Doi: 10.1002/jcsm.12048
20. Gibson DJ, Burden ST, Strauss BJ, Todd C, Lal S. The role of computed tomography in evaluating body composition and the influence of reduced muscle mass on clinical outcome in abdominal malignancy: a systematic review. Eur J Clin Nutr. 2015;69(10):1079-1086. Doi: 10.1038/ejcn.2015.32
21. Rossi F, Valdora F, Bignotti B, Torri L, Succio G, Tagliafico AS. Evaluation of body Computed Tomography-determined sarcopenia in breast cancer patients and clinical outcomes: A systematic review. Cancer Treat Res Commun. 2019;21:100154. Doi: 10.1016/j.ctarc.2019.100154
22. Zakaria HM, Massie L, Basheer A, Elibe E, Boyce-Fappiano D, Shultz L, et al. Application of Morphometrics as a Predictor for Survival in Patients with Prostate Cancer Metastasis to the Spine. World Neurosurg. 2018;114
Doi: 10.1016/j.wneu.2018.03.115
23. Santos K, Gomes F, Silva S, Silva A, Pinho C. Sarcopenia en pacientes oncológicos en tratamiento Quimioterápico. Retrieved 25 May 2022.
24. Pereira-Rodríguez J, Peñaranda-Florez D, Pereira-Rodríguez R, Pereira-Rodríguez P. Cambios hemodinámicos y calidad de vida en pacientes con cáncer de próstata luego de un entrenamiento HIIT Y MICT. Ensayo clínico aleatorizado (ONCO-EXE TRIAL). Retrieved 25 May 2022.
25. Falandry C, Stefani L, Andre L, Granger M, Barbavara C, Habchi H, et al.; PROADAPT working group. Interventions to improve physical performances of older people with cancer before complex medico-surgical procedures: Protocol for an umbrella review of systematic reviews and meta-analyses. Medicine (Baltimore). 2020;99(39). Doi: 10.1097/MD.000000000002
2. Colloca G, Di Capua B, Bellieni A, Cesari M, Marzetti E, Valentini V, et al. Musculoskeletal aging, sarcopenia and cancer. J Geriatr Oncol. 2019;10(3):504-509. Doi: 10.1016/j.jgo.2018.11.007
3. Cruz-Jentoft AJ, Bahat G, Bauer J, Boirie Y, Bruyère O, Cederholm T, et al.; Writing Group for the European Working Group on Sarcopenia in Older People 2 (EWGSOP2), and the Extended Group for EWGSOP2. Sarcopenia: revised European consensus on definition and diagnosis. Age Ageing. 2019;48(1):16-31. Doi: 10.1093/ageing/afy169
4. Peterson SJ, Braunschweig CA. Prevalence of Sarcopenia and Associated Outcomes in the Clinical Setting. Nutr Clin Pract. 2016;31(1):40-48. Doi: 10.1177/0884533615622537
5. Barret M, Antoun S, Dalban C, Malka D, Mansourbakht T, Zaanan A, et al. Sarcopenia is linked to treatment toxicity in patients with metastatic colorectal cancer. Nutr Cancer. 2014;66(4):583-589. Doi: 10.1080/01635581.2014.894103
6. da Silva JR Jr, Wiegert E, Oliveira L, Calixto-Lima L. Different methods for diagnosis of sarcopenia and its association with nutritional status and survival in patients with advanced cancer in palliative care. Nutrition. 2019;60:48-52. Doi: 10.1016/j.nut.2018.09.003
7. Pamoukdjian F, Bouillet T, Lévy V, Soussan M, Zelek L, Paillaud E. Prevalence and predictive value of pre-therapeutic sarcopenia in cancer patients: A systematic review. Clin Nutr. 2018;37(4):1101-1113. Doi: 10.1016/j.clnu.2017.07.010
8. Molina Garrido MJ, Guillén Ponce C, Fernández Félix B, Muñoz Sánchez M, Soriano Rodríguez M, Olaverri Hernández A, et al. Detección y evaluación del papel de la sarcopenia en ancianos con cáncer tratados con quimioterapia. Proyecto ONCOSARCO. Rev Esp Geriatr Gerontol. 2017;52(3):146-151. Doi: 10.1016/j.regg.2016.02.003
9. Chindapasirt J. Sarcopenia in Cancer Patients. Asian Pac J Cancer Prev. 2015;16(18):8075-8077. Doi: 10.7314/apjcp.2015.16.18.8075
10. Kazemi-Bajestani SM, Mazurak VC, Baracos V. Computed tomography-defined muscle and fat wasting are associated with cancer clinical outcomes. Semin Cell Dev Biol. 2016;54:2-10. Doi: 10.1016/j.semcdb.2015.09.001
11. da Cunha LP, Silveira MN, Mendes M, Costa FO, Macedo LT, de Siqueira NS, et al. Sarcopenia as an independent prognostic factor in patients with metastatic colorectal cancer: A retrospective evaluation. Clin Nutr ESPEN. 2019;32:107-112. Doi: 10.1016/j.clnesp.2019.04.004
12. Uchida T, Sekine R, Matsuo K, Kigawa G, Umemoto T, Kijima K, et al. Association between low preoperative skeletal muscle quality and infectious complications following gastrectomy for gastric cancer. Surg Today. 2021;51(7):1135-1143. Doi: 10.1007/s00595-020-02225-x
13. Fuggle N, Shaw S, Dennison E, Cooper C. Sarcopenia. Best Pract Res Clin Rheumatol. 2017;31(2):218-242. Doi: 10.1016/j.berh.2017.11.007
14. Robertson HL, Michel C, Bartl L, Hamilton-Reeves JM. Sarcopenia in urologic oncology: Identification and strategies to improve patient outcomes. Urol Oncol. 2020;S1078-1439(20)30197-6. Advance online publication. Doi: 10.1016/j.urolonc.2020.05.001
15. Narayan V, Harrison M, Cheng H, Kenfield S, Aggarwal R, Kwon D, et al. Improving research for prostate cancer survivorship: A statement from the Survivorship Research in Prostate Cancer (SuRECaP) working group. Urol Oncol. 2020;38(3):83-93. Doi: 10.1016/j.urolonc.2019.10.006
16. Martínez-González MA, Sánchez-Villegas A. Food patterns and the prevention of depression. Proc Nutr Soc. 2016;75(2):139-146. Doi: 10.1017/S0029665116000045
17. Shachar SS, Williams GR, Muss HB, Nishijima TF. Prognostic value of sarcopenia in adults with solid tumours: A meta-analysis and systematic review. Eur J Cancer. 2016;57:58-67. Doi: 10.1016/j.ejca.2015.12.030
18. Krznarić Ž, Bender DV, Laviano A, Cuerda C, Landi F, Monteiro R, et al. A simple remote nutritional screening tool and practical guidance for nutritional care in primary practice during the COVID-19 pandemic. Clin Nutr. 2020;39(7):1983-1987. Doi: 10.1016/j.clnu.2020.05.006
19. Malmstrom TK, Miller DK, Simonsick EM, Ferrucci L, Morley JE. SARC-F: a symptom score to predict persons with sarcopenia at risk for poor functional outcomes. J Cachexia Sarcopenia Muscle. 2016;7(1):28-36. Doi: 10.1002/jcsm.12048
20. Gibson DJ, Burden ST, Strauss BJ, Todd C, Lal S. The role of computed tomography in evaluating body composition and the influence of reduced muscle mass on clinical outcome in abdominal malignancy: a systematic review. Eur J Clin Nutr. 2015;69(10):1079-1086. Doi: 10.1038/ejcn.2015.32
21. Rossi F, Valdora F, Bignotti B, Torri L, Succio G, Tagliafico AS. Evaluation of body Computed Tomography-determined sarcopenia in breast cancer patients and clinical outcomes: A systematic review. Cancer Treat Res Commun. 2019;21:100154. Doi: 10.1016/j.ctarc.2019.100154
22. Zakaria HM, Massie L, Basheer A, Elibe E, Boyce-Fappiano D, Shultz L, et al. Application of Morphometrics as a Predictor for Survival in Patients with Prostate Cancer Metastasis to the Spine. World Neurosurg. 2018;114
Doi: 10.1016/j.wneu.2018.03.115
23. Santos K, Gomes F, Silva S, Silva A, Pinho C. Sarcopenia en pacientes oncológicos en tratamiento Quimioterápico. Retrieved 25 May 2022.
24. Pereira-Rodríguez J, Peñaranda-Florez D, Pereira-Rodríguez R, Pereira-Rodríguez P. Cambios hemodinámicos y calidad de vida en pacientes con cáncer de próstata luego de un entrenamiento HIIT Y MICT. Ensayo clínico aleatorizado (ONCO-EXE TRIAL). Retrieved 25 May 2022.
25. Falandry C, Stefani L, Andre L, Granger M, Barbavara C, Habchi H, et al.; PROADAPT working group. Interventions to improve physical performances of older people with cancer before complex medico-surgical procedures: Protocol for an umbrella review of systematic reviews and meta-analyses. Medicine (Baltimore). 2020;99(39). Doi: 10.1097/MD.000000000002
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Publicado
jun 28, 2024
Detalles del artículo
Cómo citar
Aguilera-Jinesta, T., & Uclés-Villalobos, V. (2024). Sarcopenia en paciente oncológico: revisión de literatura . Revista Hispanoamericana De Ciencias De La Salud, 10(1), 40–47. https://doi.org/10.56239/rhcs.2024.101.715
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Biografía del autor/a
MD Teresita Aguilera-Jinesta, Servicio de Medicina Física y Rehabilitación, Hospital Dr. Rafael Ángel Calderón Guardia. Caja Costarricense de Seguro Social, Costa Rica.
Médico Residente
MD Vanessa Uclés-Villalobos, Servicio de Medicina Física y Rehabilitación, Hospital Dr. Rafael Ángel Calderón Guardia. Caja Costarricense de Seguro Social, Costa Rica.
Médico Especialista en Medicina Física y Rehabilitación.